High-resolution NMR-MOUSE®

Portable single-sided nuclear magnetic resonance (NMR) magnets used for non-destructive studies of large samples are believed to generate inherently inhomogeneous magnetic fields. Recently we demonstrated that the field of an open magnet can be shimmed to high homogeneity in a large volume external to the sensor. This technique allowed us to measure localized high-resolution proton spectra outside a portable open magnet with a spectral resolution better than one parts per million. The generation of these experimental conditions also simplifies the implementation of powerful methodologies as multidimensional NMR spectroscopy and imaging.

The HR10 NMR-MOUSE® has been optimized to achieve a resolution better than 1 ppm in a volume of about 10 mm3. The magnet generates a magnetic field strength of 0.22 T, corresponding to a resonance frequency for protons of about 10 MHz. The high sensitivity obtained thanks to the relatively large volume size enables to acquire spectra of liquids in very short acquisition times, particularly useful for on-line chemical analysis of large samples.